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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KB2
All Species:
5.45
Human Site:
T443
Identified Species:
8.57
UniProt:
Q9UBS0
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBS0
NP_003943.2
482
53483
T443
S
P
S
L
P
E
P
T
E
L
P
L
P
P
L
Chimpanzee
Pan troglodytes
XP_001172909
482
53404
T443
S
P
S
L
P
E
P
T
E
L
P
L
P
P
V
Rhesus Macaque
Macaca mulatta
XP_001117937
512
56562
M470
S
P
S
L
P
E
P
M
E
P
P
L
P
P
L
Dog
Lupus familis
XP_851971
482
53401
M441
S
S
G
P
P
E
P
M
E
P
P
L
P
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1M4
485
53520
M443
S
P
G
P
P
E
P
M
E
P
S
L
P
P
L
Rat
Rattus norvegicus
P67999
525
59113
N467
G
A
S
A
S
T
A
N
P
Q
T
P
V
E
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509850
482
54026
T424
G
A
S
A
S
T
V
T
T
Q
P
P
V
E
Y
Chicken
Gallus gallus
P18652
752
84421
H454
S
V
C
K
R
C
I
H
K
T
T
N
M
E
Y
Frog
Xenopus laevis
P10665
733
82620
K436
V
C
K
R
C
V
H
K
G
T
N
M
E
Y
A
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
R440
I
C
K
R
C
I
H
R
V
T
A
M
E
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
P1074
V
L
M
Q
Q
L
P
P
P
G
D
N
V
V
A
Honey Bee
Apis mellifera
XP_395876
456
51514
R418
S
P
R
R
G
N
M
R
G
F
S
P
R
T
T
Nematode Worm
Caenorhab. elegans
Q21734
784
88102
R478
C
Q
M
K
A
T
R
R
K
Y
A
V
K
I
V
Sea Urchin
Strong. purpuratus
XP_781234
487
53968
K448
F
D
E
D
L
L
T
K
P
S
S
S
R
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
M432
F
D
K
C
W
T
D
M
S
V
L
D
S
P
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
91.8
95
N.A.
92.9
65.7
N.A.
70.9
30
30.5
30.2
N.A.
21.1
56.8
29.9
60.9
Protein Similarity:
100
99.7
92.5
96.6
N.A.
95
76
N.A.
80.9
42.8
42.5
43.2
N.A.
28.3
70.7
43.1
74.5
P-Site Identity:
100
93.3
86.6
66.6
N.A.
66.6
6.6
N.A.
20
6.6
0
0
N.A.
6.6
13.3
0
0
P-Site Similarity:
100
100
86.6
66.6
N.A.
66.6
6.6
N.A.
20
13.3
6.6
6.6
N.A.
6.6
13.3
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
14
7
0
7
0
0
0
14
0
0
7
34
% A
% Cys:
7
14
7
7
14
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
14
0
7
0
0
7
0
0
0
7
7
0
0
0
% D
% Glu:
0
0
7
0
0
34
0
0
34
0
0
0
14
20
0
% E
% Phe:
14
0
0
0
0
0
0
0
0
7
0
0
0
7
0
% F
% Gly:
14
0
14
0
7
0
0
0
14
7
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
14
7
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
7
7
0
0
0
0
0
0
7
0
% I
% Lys:
0
0
20
14
0
0
0
14
14
0
0
0
7
0
0
% K
% Leu:
0
7
0
20
7
14
0
0
0
14
7
34
0
0
27
% L
% Met:
0
0
14
0
0
0
7
27
0
0
0
14
7
0
0
% M
% Asn:
0
0
0
0
0
7
0
7
0
0
7
14
0
0
0
% N
% Pro:
0
34
0
14
34
0
40
7
20
20
34
20
34
40
0
% P
% Gln:
0
7
0
7
7
0
0
0
0
14
0
0
0
0
0
% Q
% Arg:
0
0
7
20
7
0
7
20
0
0
0
0
14
0
0
% R
% Ser:
47
7
34
0
14
0
0
0
7
7
20
7
7
0
0
% S
% Thr:
0
0
0
0
0
27
7
20
7
20
14
0
0
7
7
% T
% Val:
14
7
0
0
0
7
7
0
7
7
0
7
20
7
14
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
7
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _